| Title |
Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits
|
|---|---|
| Published in |
Nature Communications, October 2016
|
| DOI | 10.1038/ncomms13034 |
| Pubmed ID | |
| Authors |
Noham Wolpe, James N. Ingram, Kamen A. Tsvetanov, Linda Geerligs, Rogier A. Kievit, Richard N. Henson, Daniel M. Wolpert, James B. Rowe |
| Abstract |
The control of voluntary movement changes markedly with age. A critical component of motor control is the integration of sensory information with predictions of the consequences of action, arising from internal models of movement. This leads to sensorimotor attenuation-a reduction in the perceived intensity of sensations from self-generated compared with external actions. Here we show that sensorimotor attenuation occurs in 98% of adults in a population-based cohort (n=325; 18-88 years; the Cambridge Centre for Ageing and Neuroscience). Importantly, attenuation increases with age, in proportion to reduced sensory sensitivity. This effect is associated with differences in the structure and functional connectivity of the pre-supplementary motor area (pre-SMA), assessed with magnetic resonance imaging. The results suggest that ageing alters the balance between the sensorium and predictive models, mediated by the pre-SMA and its connectivity in frontostriatal circuits. This shift may contribute to the motor and cognitive changes observed with age. |
X Demographics
The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 7 | 25% |
| United States | 3 | 11% |
| Spain | 2 | 7% |
| Germany | 1 | 4% |
| France | 1 | 4% |
| Japan | 1 | 4% |
| Canada | 1 | 4% |
| Russia | 1 | 4% |
| Netherlands | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 10 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 61% |
| Scientists | 8 | 29% |
| Practitioners (doctors, other healthcare professionals) | 2 | 7% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 183 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 38 | 21% |
| Student > Ph. D. Student | 37 | 20% |
| Student > Master | 24 | 13% |
| Other | 12 | 6% |
| Student > Bachelor | 10 | 5% |
| Other | 33 | 18% |
| Unknown | 31 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 46 | 25% |
| Psychology | 37 | 20% |
| Engineering | 15 | 8% |
| Agricultural and Biological Sciences | 11 | 6% |
| Medicine and Dentistry | 9 | 5% |
| Other | 17 | 9% |
| Unknown | 50 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2023.
All research outputs
#2,207,086
of 25,584,565 outputs
Outputs from Nature Communications
#27,704
of 57,717 outputs
Outputs of similar age
#37,511
of 329,789 outputs
Outputs of similar age from Nature Communications
#446
of 909 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 57,717 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.5. This one has gotten more attention than average, scoring higher than 51% of its peers.
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We're also able to compare this research output to 909 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.